posted on 2023-12-21, 18:03authored byMeiqun Lu, Kailun Chen, Tao Wu, Hu Cai
A method is presented for decarboxylative alkoxy–alkoxycarbonylation
of various alkenes with alcohols by electrochemical anodic oxidation
of monopotassium ethyloxalate salts with good functional group compatibility.
The reaction involves anodic oxidation to form an acyl radical, followed
by addition to an olefin to yield a new alkyl radical, which is anodically
oxidized to a carbon cation and captured by alcohols to afford β-alkoxyalkanoates.
Adding catalytic amounts of ammonium iodide enhanced the efficiency
of the reactions.