pone.0253260.s004.pdf (250.84 kB)
Effects of mut-sFasL on caspase 3/7 activity.
journal contribution
posted on 2021-06-17, 17:30 authored by Osamu Kajikawa, Raquel Herrero, Yu-Hua Chow, Chi F. Hung, Gustavo Matute-BelloEffect of increasing concentrations of mut-sFasL on caspase 3/7 activity (white violin bars) or in combination with a fixed concentration of WT sFasL. We observed that only at the highest dose of 2430 ng/mL, corresponding to the 1:81 WT:mut sFasL molar ratio in Fig 3, the mut-sFasL leads to intrinsic caspase-3/7 activation.
(PDF)
History
Usage metrics
Categories
Keywords
alveolar epithelial cellsacidintratracheal Escherichia coli lipo...Fas ligandFas-sensitive Jurkat T-cell lineT-cell line Jurkatregiontype protein functionmut-sFasL attenuated WT-sFasL functionresponse 24 hoursmice 24 hoursbioactivitycaspase -3 activityairway epithelial cellslipopolysaccharide-induced lung injury
Licence
Exports
RefWorks
BibTeX
Ref. manager
Endnote
DataCite
NLM
DC