ppat.1011781.s004.pdf (656.5 kB)
Effect of GK2 on HCMV protein expression in infected cells.
journal contribution
posted on 2023-11-17, 18:40 authored by Han Chen, Ming F. Lye, Christoph Gorgulla, Scott B. Ficarro, Gregory D. Cuny, David A. Scott, Fan Wu, Paul W. Rothlauf, Xiaoou Wang, Rosio Fernandez, Jean M. Pesola, Sorin Draga, Jarrod A. Marto, James M. Hogle, Haribabu Arthanari, Donald M. CoenHFF cells were mock infected or infected with WT HCMV at an MOI of 1. Following absorption, medium containing either DMSO or 10 μM GK2 was added. At 72 hpi, cells were lysed, proteins resolved using SDS-PAGE, and the expression of the viral proteins indicated to the left was assessed by immunoblotting. Similar results were obtained in a second independent experiment.
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