pone.0293731.s015.docx (36.75 kB)
Druggability analysis of shortlisted non-human homologous pathogenic essential proteins.
journal contribution
posted on 2024-01-19, 18:55 authored by Sara Aiman, Qurrat ul Ain Farooq, Zhongjie Han, Muneeba Aslam, Jilong Zhang, Asifullah Khan, Abbas Ahmad, Chunhua Li, Yasir AliDruggability analysis of shortlisted non-human homologous pathogenic essential proteins.
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predict potent inhibitorsincreasing antimicrobial resistanceimmune simulation analysesidentify new strategiesdruggable molecule databasesdiv >< pchallenging worldwide owing965 druggable moleculeidentify promising vaccinetherapeutic targets prioritizedcore proteome databased virtual screeningalternative drug targetsclostridium difficile difficile designed vaccinec vaccinomics approachesurgent threatsubtractive proteomicsmortality ratesimmunological analysishigh rateshigh morbidityexperimental validationdrug candidatesdependent nitroreductasecurrent studyconserved residuescell epitopes
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