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Disorder prediction in AR and KDM4A.

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posted on 2022-01-05, 18:26 authored by Carlos M. Roggero, Victoria Esser, Lingling Duan, Allyson M. Rice, Shihong Ma, Ganesh V. Raj, Michael K. Rosen, Zhi-Ping Liu, Josep Rizo

A. Amino acid sequence of the human androgen receptor N-terminal domain. The poly-Q is highlighted in yellow. B, C. Intrinsically disordered scores predicted for human AR (B) and human KDM4A (C) by the disordered prediction tool IUPred3 [Erdos G, Pajkos M, Dosztanyi Z. IUPred3: prediction of protein disorder enhanced with unambiguous experimental annotation and visualization of evolutionary conservation. Nucleic Acids Res. 2021;49(W1):W297-W303].

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