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Designing a molecular analysis of clonality in tumours

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journal contribution
posted on 15.11.2012, 23:55 authored by Salvador J. Diaz-CanoSalvador J. Diaz-Cano

Clonality analysis is used to test malignant transformation and tumour progression.
X-chromosome linked clonality assays have been employed for this purpose, but are subject
to certain technical limitations. This paper reviews the issues involved and the controls that
are necessary to ensure valid interpretation of such analyses.

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