pone.0257628.s006.docx (38.26 kB)
Derivations of indirect, direct and total effects.
journal contribution
posted on 2021-10-12, 17:24 authored by Jian Wang, Jing Ning, Sanjay Shete(DOCX)
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women 8217proposed approach providespolymorphic loci ),commonly used modelmediation model cannotproposed overall measuresadditive genetic modelmediation modelgenetic modelwidely usedoverall contributionmediation modelsgenetic variantsgenetic studiestotal effectsthus modificationstatistical methodmediating effectexisting approachesempirical performanceeither recessivedominant modelsdifferent valuesdetect effectsclinical phenotypes
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