Correlation between neutralising antibody titre against Wuhan-hu-1 and variants of concern.

Davis, Chris; Logan, Nicola; Tyson, Grace; Orton, Richard; Harvey, William T.; Perkins, Jonathan S.; Mollett, Guy; Blacow, Rachel M.; Peacock, Thomas P.; Barclay, Wendy S.; Cherepanov, Peter; Palmarini, Massimo; Murcia, Pablo R.; Patel, Arvind H.; Robertson, David L.; Haughney, John; Thomson, Emma C.; Willett, Brian J.

doi:10.1371/journal.ppat.1010022.s006

sorry, we can't preview this file

ppat.1010022.s006.docx (255.46 kB)

Correlation between neutralising antibody titre against Wuhan-hu-1 and variants of concern.

journal contribution

posted on 2021-12-02, 19:04 authored by Chris Davis, Nicola Logan, Grace Tyson, Richard Orton, William T. Harvey, Jonathan S. Perkins, Guy Mollett, Rachel M. Blacow, Thomas P. Peacock, Wendy S. Barclay, Peter Cherepanov, Massimo Palmarini, Pablo R. Murcia, Arvind H. Patel, David L. Robertson, John Haughney, Emma C. Thomson, Brian J. Willett

Antibody responses measured by pseudotype-based neutralisation assay against Wuhan-hu-1 were compared with those against B.1.617.1, B.1.617.2 and B.1.351. Responses were compared for A) BNT162b2 1 dose, B) BNT162b2 2 doses, C) ChAdOx1 1 dose and D) ChAdOx1 2 doses. Correlations between groups were evaluated and non-parametric Spearman correlation coefficients calculated.

(DOCX)