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Contribution of COSMIC Single Base Substitution (SBS) signatures to S. pombe mutational patterns.

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posted on 2021-07-06, 17:33 authored by Ignacio Soriano, Enrique Vazquez, Nagore De Leon, Sibyl Bertrand, Ellen Heitzer, Sophia Toumazou, Zhihan Bo, Claire Palles, Chen-Chun Pai, Timothy C. Humphrey, Ian Tomlinson, Sue Cotterill, Stephen E. Kearsey

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    PLOS Genetics

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    RPArad 3 inactivationT T G transitionsPOLEexonuclease domain mutationstranslesion synthesis polymeraseTCTTCGDNA replication SomaticPOLE-Ppol 2-P variantT C Gtranslesion synthesis polymerasesfission yeastreplicative DNA polymerase εWhole-genome sequencing analysispol 2-P mutationEDMpol 2-P hypermutationT C TPfh 1 helicase286Rpol 2-P allele

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