pone.0294176.s008.pdf (78.76 kB)
Confirmation of CD4 T-cell depletion.
journal contribution
posted on 2023-12-27, 18:32 authored by Liat Bar-On, Hani Dekel, Moshe Aftalion, Theodor Chitlaru, Noam ErezAnimals were treated with anti CD4 depleting antibody one day before infection and in every other day post infection. CD4 T-cell depletion was confirmed by flow cytometry.
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novel murine linefuture vaccine designdraining lymph nodealso significantly impactedwhereas humoral responses2 susceptible k18xlink "> sarsconsequent impaired cd8batf3 deficient micedependent dendritic cells2 viral load2 specific cd8specific cd8severely impairedregulating cd8dependent dccell responsesspecific role2 infectionsignificant increaseresults underscoreregulating sarsmay contributelargely unknownindependently corroboratedhace2 transgenicessential roleeffector phasecell responsecell immunityadditional covidadapted sars
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