pgen.1009870.s006.pdf (5.45 MB)
Condensin II proteins are required for chromocenter and centromere cluster dissociation in somatic cyst cells.
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posted on 2021-10-20, 17:36 authored by Luisa Vernizzi, Christian F. Lehner(A—C) Time-lapse imaging of His2Av-mRFP and Cenp-A/Cid-EGFP was applied for analysis of cyst cells in late spermatocyte cysts in (A) control (+ / +), (B) Cap-D3 mutants (Cap-D3EY/ Df), and (C) Cap-H2 mutants (Cap-H2cc3/ Df). Time (min:sec) is indicated relative to the onset of imaging. Scale bars = 3 μm. See S6 Fig for further explanations.
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interphase might requirefirst meiotic divisionexcessive chromosome missegregationdiv >< padditional force generatorsalternative homolog conjunctionh2 precluded conjunctioncondensin ii subunitschromosome territory formationdrosophila melanogaster occasional chromocenter disruptionabolish chromocenter disruptionhomologous associations ariseterritory formationcondensin iidrosophila homologous chromosomeshomolog pairingh2 chromocenter persistencespecial systemresults indicateremarkable separationrandom segregationpericentromeric heterochromatinmoved apartmolecular basislarge blocksgenome ploidyforces remainsf actindna satellitesconjoins homologscentromere clusterscentromere clusteringbivalent individualizationautosomal homologsapplied time
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