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Cleavage rates to LOF in females.

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posted on 2021-02-18, 19:53 authored by Georg Oberhofer, Tobin Ivy, Bruce A. Hay

Shown are the genotype frequencies in the offspring of a cross between heterozygous Cleaver/+;Rescuetko/+ virgins and w1118 males. All of the offspring carried the dominant td-tomato marker of Rescuetko.

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    PLOS Genetics

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    Keywords

    recoded versiongene drive Gene drive elementsDNA sequence-modifying enzymedrive strengthrecombination frequencyLOF allelesCas 9-dependent mannertrait spreadnovel pointCas 9drive mechanismsSelf-sustaining Cleaveobservations showsplit ClvRLOF allele creationfuture driveCargoCas 9 transiently experiences driveCas 9 decreasesuse modelingRescuelinkage disequilibriumCas 9 frequency

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