pone.0296502.s002.pdf (769.03 kB)
Circulating Vpr under HIV viremic conditions and oncovirus-related malignancies.
journal contribution
posted on 2024-01-02, 18:59 authored by Akihiro Matsunaga, Naokatsu Ando, Yuko Yamagata, Mari Shimura, Hiroyuki Gatanaga, Shinichi Oka, Yukihito Ishizaka(A) Stacked bar chart showing the proportion of Vpr-positive samples in HIV patients with aviremia (Av) and viremia (V). Black bar, Vpr positivity. White bar, Vpr negativity. Violin plot showing the distribution of Vpr concentrations (ng/mL). Dotted line is the detection limit of Vpr (3.8 ng/mL). (B) The detection frequency of Vpr in patients with AIDS-defining malignancies (ADM) and non-AIDS defining malignancies (NADM). (C) The detection frequency of Vpr in patients with virus-related (VR) and virus-unrelated malignancies (VUR).
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viral protein rlinked immunosorbent assayshuman immunodeficiency virustumor group (<030 ), althoughxlink "> vpr6 %, respectivelymatched tumor grouptumor group ),tumor group vstumor group comparedhiv patients comprisingalso detected anti6 %) (<hiv patients (<1 associated malignanciesvpr levels (<tumor grouptumors (<tumor occurrencedetected vpr6 ),ml ),002 ),patients positive126 patientsvpr immunoglobulinvpr igg6 level6 couldsignificantly higherrisk factorspositive linkmatched noninfected individualshigher frequencyfree enzymefirst selecteddifferent distributiondetection limitadvanced cases96 samples372 ).3 %)010 ).001 ),
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