Chronic disease associations with COVID-19 predicted cases and COVID-19 positive cases.

van Blokland, Irene V.; Lanting, Pauline; Ori, Anil P. S.; Vonk, Judith M.; Warmerdam, Robert C. A.; Herkert, Johanna C.; Boulogne, Floranne; Claringbould, Annique; Lopera-Maya, Esteban A.; Bartels, Meike; Hottenga, Jouke-Jan; Ganna, Andrea; Karjalainen, Juha; Hayward, Caroline; Fawns-Ritchie, Chloe; Campbell, Archie; Porteous, David; Cirulli, Elizabeth T.; Barrett, Kelly M. Schiabor; Riffle, Stephen; Bolze, Alexandre; White, Simon; Tanudjaja, Francisco; Wang, Xueqing; Ramirez, Jimmy M.; Lim, Yan Wei; Lu, James T.; Washington, Nicole L.; de Geus, Eco J. C.; Deelen, Patrick; Boezen, H. Marike; Franke, Lude H.

doi:10.1371/journal.pone.0255402.s004

pone.0255402.s004.pdf (153.81 kB)

Chronic disease associations with COVID-19 predicted cases and COVID-19 positive cases.

journal contribution

posted on 2021-08-11, 17:31 authored by Irene V. van Blokland, Pauline Lanting, Anil P. S. Ori, Judith M. Vonk, Robert C. A. Warmerdam, Johanna C. Herkert, Floranne Boulogne, Annique Claringbould, Esteban A. Lopera-Maya, Meike Bartels, Jouke-Jan Hottenga, Andrea Ganna, Juha Karjalainen, Caroline Hayward, Chloe Fawns-Ritchie, Archie Campbell, David Porteous, Elizabeth T. Cirulli, Kelly M. Schiabor Barrett, Stephen Riffle, Alexandre Bolze, Simon White, Francisco Tanudjaja, Xueqing Wang, Jimmy M. Ramirez III, Yan Wei Lim, James T. Lu, Nicole L. Washington, Eco J. C. de Geus, Patrick Deelen, H. Marike Boezen, Lude H. Franke

Fisher’s exact test shows a Bonferroni significant positive correlation between “Neurological disease”, “Psychological disease”, “Chronic muscle disease”, “Cancer” and “Lung disease” patients and COVID-19 predicted cases. This association is not present for positive COVID-19 cases. Applying generalised linear models with “age”, “sex” and “bmi” as covariates, instead of Fishers exact tests, does not change which diseases are Bonferroni significant and which are not.

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