pone.0278569.s003.docx (32.47 kB)
Chlorhexidine and octenidine minimal inhibitory concentrations (MIC) of bacterial isolates from clinical samples in percentage of extraction solution.
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posted on 2022-12-14, 18:28 authored by Luisa A. Denkel, Tobias S. Kramer, Frank Schwab, Jennifer Golembus, Solvy Wolke, Petra Gastmeier, Christine GeffersMedian MIC (MIC50) with inter quartile ranges (IQR) and MIC90 are given in in [%] of extraction solution and are reported for Staphylococcus aureus, coagulase-negative staphylococci, Escherichia coli, Klebsiella spp. and Pseudomonas aeruginosa stratified by study group (chlorhexidine, octenidine, routine care) and period (baseline = prior to the intervention period, intervention = at the end of the intervention period).
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routinely used 2routine antiseptic bathingregistration number drks00010475intensive care unitsimpregnated wash clothsextraction solutions usedantiseptic bathing may3 days lengthstaphylococcus aureus pseudomonas aeruginosa escherichia coli antiseptic bathing groupsreduced phenotypic susceptibilities155 ), coagulaseoctenidine wash mittsoctenidine extraction solutionsthree armed clustericus 12 monthsattributable bacterial isolatestwo intervention groupsbacterial isolatesklebsiella intervention groupsphenotypic susceptibility227 ),122 ),octenidine susceptibilityoctenidine collectedxlink ">unintended consequencestracheal aspiratepathogens includednegative staphylococciml derivedintervention periodestimated concentrationsconducted withincollected priorclinical samplesanalysis aimed2016 ).136 ).&# 956&# 8805
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