posted on 2024-02-23, 18:13authored byNeeraj Bangruwa, Mayank Tiwari, Ankur Shandilya, Rafael Gutierrez, Mayra Peralta, Solmar Varela, Gianaurelio Cuniberti, Debabrata Mishra
The chiral-induced spin selectivity (CISS) effect can
distinguish
between the spin of electrons as they pass through chiral molecules
by backscattering one of the spin components. Herein, we explore the
role of the CISS effect in time-correlated single-photon counting
measurements to detect DNA hybridization. We observe that the average
lifetime of optical excited states of quantum dots attached to double-stranded
DNA (dsDNA) varies with directions of the applied magnetic field.
Specifically, the difference in the nonradiative average decay lifetime
for the two orientations of the applied magnetic field is 2.21 ns
in the case of hybridized strands, which is 130 times higher than
that observed with quantum dots attached to single-strand DNA. Additionally,
we investigate the application of Fourier transform infrared (FTIR)
spectroscopy for detecting double-stranded DNA in the presence of
a magnetic field, establishing a theoretical framework to substantiate
the experimental evidence of magnetic field-dependent FTIR spectroscopy
for dsDNA.