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Canonical pathway analysis of signaling pathways.

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posted on 2021-08-24, 17:32 authored by Eun Na Kim, Jiyoung Yu, Joon Seo Lim, Hwangkyo Jeong, Chong Jai Kim, Jae-Sung Choi, So Ra Kim, Hee-Sung Ahn, Kyunggon Kim, Se Jin Oh

IPA bio function analysis (QIAGEN Inc., https://www.qiagenbioinformatics.com/products/ingenuity-pathway-analysis/) was carried out to assemble a network between (A) LXR/RXR activation, (B) coagulation system, (C) acute phase response signaling, (D) extrinsic prothrombin activation pathway, (E) intrinsic prothrombin activation pathway, (F) atherosclerosis signaling, and (G) complement system of the proteins differentially abundant in the AAA-high mCRP group. Red and green colors represent the measured levels of increased and decreased molecules, respectively. Orange and blue colors represent the predicted activation or inhibition of molecules or bio functions, respectively.

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