pgen.1010050.s005.pdf (398.51 kB)
Candidate functional SNPs-mediated disruption of transcription factor motifs.
journal contribution
posted on 2022-02-02, 18:40 authored by Xiaoqing Cheng, Fenglan Zhang, Jingwen Gong, Yige Li, Dan Zhou, Jing Wang, Eu Gene Vong, Ying Yuan, Maode Lai, Dandan Zhang(PDF)
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wide association studiesstrong linkage disequilibriumpromising therapeutic target160 susceptibility locispecific enhancer activitymodulating enhancer activityputative functional varianteqtl association datacomprehensive functional annotationrelated gwas signalsdiv >< p1 might servepotential causal variantspotential functional variantscrc susceptibility snpsfunctional annotationfunctional variantsregulatory potentialcrc activitydata suggestc datathus indicatingsmad7 rs72917785 ),remain unclearpromoted malignancypoor prognosisoffer guidesmrna levelsmodest inhibitionlipg intron 3firstly conductedexhibited allelecrc cellscrc ).colorectal canceralso verified1 associated
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