posted on 2024-01-12, 07:00authored byJia Yang, Jian-Pei Zhang, Rong-Mei Gao, Wen-Rui Li, Jing-Yu Zhang, Qian-Ru Wang, Mi Li, Hai-Qiang Wang, Guo-Zhu Su, Li Li, Yu-Huan Li, Ru-Bing Wang, Xiao-Jing Wang, Shuang-Gang Ma
Three new cadinane sesquiterpenes (1–3) and three known sesquiterpenes were isolated from the stems and branches of Illicium ternstroemioides A. C. Smith. The structures of the new compounds were elucidated by extensive analysis of spectroscopic and HRESIMS data. The structures of illiternins A–C (1–3) were confirmed by single crystal X-ray diffraction, allowing for the determination of their absolute configurations. Compounds 3 and 6 exhibited antiviral activity against Coxsackievirus B3 with IC50 values of 33.3 and 57.7 μM, respectively.
Funding
This work was funded by the National Natural Science Foundation of China [22177135].