pgen.1009870.s005.pdf (2.32 MB)
Behavior of heterochromatin proteins D1 and Prod in Cap-H2cc3 mutant spermatocytes.
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posted on 2021-10-20, 17:36 authored by Luisa Vernizzi, Christian F. Lehner(A, B) Whole mount preparations of testes expressing D1-sfGFP were labeled with anti-Prod, anti-Lamin Dm0 and a DNA stain. Testes were either from control males (+ / +) of from Cap-H2cc3/ Df(3R)Exel6159 mutants. (A) Testis tip regions. (B) High magnification view with spermatogonial cells (upper region) and S1/2 spermatocytes (lower region) with high and low levels of D1-sfGFP, respectively. Scale bars = 20 μm (A) and 10 μm (B).
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interphase might requirefirst meiotic divisionexcessive chromosome missegregationdiv >< padditional force generatorsalternative homolog conjunctionh2 precluded conjunctioncondensin ii subunitschromosome territory formationdrosophila melanogaster occasional chromocenter disruptionabolish chromocenter disruptionhomologous associations ariseterritory formationcondensin iidrosophila homologous chromosomeshomolog pairingh2 chromocenter persistencespecial systemresults indicateremarkable separationrandom segregationpericentromeric heterochromatinmoved apartmolecular basislarge blocksgenome ploidyforces remainsf actindna satellitesconjoins homologscentromere clusterscentromere clusteringbivalent individualizationautosomal homologsapplied time
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