ppat.1009519.s008.docx (23.33 kB)
Backbone resonance assignment and NH RDCs of full-length E protein in HPC micelles.
journal contribution
posted on 2021-05-18, 17:36 authored by Sang Ho Park, Haley Siddiqi, Daniela V. Castro, Anna A. De Angelis, Aaron L. Oom, Charlotte A. Stoneham, Mary K. Lewinski, Alex E. Clark, Ben A. Croker, Aaron F. Carlin, John Guatelli, Stanley J. Opella(DOCX)
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activity SARS-CoV -2SARS-CoV -2 E proteinchemical shift indexchemical shift changesamiloride pyrazine ringCOVIDE protein spectraDMAN-terminal transmembrane domaininhibitor binding siteion channel inhibitorsHMAdipolar wave plotsbinding sitetransmembrane domain exhibits ion c...EIPAstructure-based drug discoveryVero E 6 cellsNMRchemical shift perturbations75- residue integral membrane proteinE proteinN 15A mutationC-terminal cytoplasmic domainSARS-CoV -2 envelope protein
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