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Associations of adipose tissue biomarkers and T2D incidence in participants with prediabetes (supplementary analysis).

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posted on 2021-07-09, 18:38 authored by Farhad Pishgar, Mahsima Shabani, Thiago Quinaglia A. C. Silva, David A. Bluemke, Matthew Budoff, R Graham Barr, Matthew A. Allison, Alain G. Bertoni, Wendy S. Post, João A. C. Lima, Shadpour Demehri

*Models did not meet the proportional hazard assumption. Model 0: unadjusted. Model 1: adjusted for categorical age, sex, race/ethnicity, smoking status, alcohol drinking status, physical activity, TG, HDL cholesterol, and hypertension. In this supplementary analysis, Cox proportional hazard models were used to study the associations between adipose tissue biomarkers and T2D incidence in participants with prediabetes at baseline. Reported p-values were corrected for multiple comparisons. BMI, body mass index; CI, confidence interval; HDL, high-density lipoprotein; HOMA-IR, homeostatic model assessment–insulin resistance; HR, hazard ratio; HU, Hounsfield unit; IMAT, intermuscular adipose tissue; PM, pectoralis muscle; PY, person-year; SAT, subcutaneous adipose tissue; SD, standard deviation; T2D, type 2 diabetes; TG, triglyceride; Waist C., waist circumference.

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