pone.0259641.s001.docx (42.7 kB)
An exploratory clinical trial of prophylactic antimicrobial administration once before treatment in percutaneous radiofrequency ablation of hepatic malignancies.
journal contribution
posted on 2021-11-19, 18:24 authored by Ryo Nakagomi, Ryosuke Tateishi, Shintaro Mikami, Taijiro Wake, Mizuki Nishibatake Kinoshita, Takuma Nakatsuka, Tatsuya Minami, Masaya Sato, Koji Uchino, Kenichiro Enooku, Hayato Nakagawa, Yoshinari Asaoka, Shuichiro Shiina, Kazuhiko Koike(DOCX)
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sided binomial testobserved following 4maximal tumor diameteradjusted hazard ratio53 &# 8211multivariable analysis indicatedinfectious complications related766 rfa treatments763 rfa treatments547 rfa treatmentsnew antibiotic protocolsignificant risk factorsapril 2012 onwardsantibiotics 663 patients usingsingle administration protocolinfectious complicationsnew protocolsingle administrationrisk factorsinterim analysissingle vscontinuous administrationapril 1revised protocolxlink ">upper limitsignificantly increaserespectively ).radiofrequency ablationprospective studyprophylactic antibioticsprespecified limitpatients usingnovember 30march 2012liver tumorshistorical controlconfidence intervalbegan usingacceptably low52 %).355 patients
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