pone.0258891.s006.docx (17.67 kB)

Allelic profiles of Leptospira in human clinical samples.

journal contribution

posted on 2021-10-20, 17:32 authored by Marjo V. Mendoza, Windell L. Rivera

Exact allele matches are shown for samples POM01, POM07, POM18, POM19, POM20 and POM23 partial profiles.—indicates no amplification or ambiguous sequences. *Nearest ST match to POM37 allelic profile. Numbers inside () show corresponding allele of nearest ST match to POM37.

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targeting 23s rrna reduced scheme addressed phylogenetic analysis confirmed one sample cannot method often used loci genetic profile clinically diagnosed cases challenges often encountered allelic profiles identified 16s rrna (<disease epidemiology specifically multilocus sequence typing div >< p simplified mlst scheme human leptospirosis cases rapid direct typing philippines rapid typing direct typing disease surveillance molecular typing rrs2 mrea lipl41 lipl32 leptospira l interrogans adk two serovars tertiary hospital serovar manilae serological tests serogroup pyrogenes routinely done public health potential alternative positive samples pathogen transmission nine positives new st monitor occurrence mlst schemes major threat interpretable data host specificity hospital settings could lead clinical specimens clinical samples clearly differentiated blood samples also aid

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