figshare
Browse
13058_2021_1387_MOESM4_ESM.pdf (73.71 kB)

Additional file 4 of PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors

Download (73.71 kB)
journal contribution
posted on 2021-01-23, 00:46 authored by Feng Bai, Shiqin Liu, Xiong Liu, Daniel P. Hollern, Alexandria Scott, Chuying Wang, Lihan Zhang, Cheng Fan, Li Fu, Charles M. Perou, Wei-Guo Zhu, Xin-Hai Pei
Additional file 4 Loss of Brca1 activates Pdgfrβ-Pkcα signaling and EMT in mammary tumors. Mammary tumors spontaneously developed in p18-/- and p18-/-;Brca1MGKO mice were analyzed by western blot.

Funding

National Natural Science Foundation of China Guangdong Provincial Science and Technology Program High Energy Physics Group, University of Mississippi (US) Natural Science Foundation of Guangdong Province DOD Idea Expansion Award American Cancer Society

History

Usage metrics

    Breast Cancer Research

    Categories

    Keywords

    BRCA1PDGFRβEMTMammary tumorTargeted therapy

    Licence

    CC BY + CC0

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC