13075_2021_2670_MOESM3_ESM.docx (32.8 kB)
Additional file 3 of WNT16 elevation induced cell senescence of osteoblasts in ankylosing spondylitis
journal contribution
posted on 2021-12-09, 04:26 authored by Sungsin Jo, Subin Weon, Bora Nam, Mi-Ae Jang, Hyundeok Kang, Tae-Jong Kim, Ye-Soo Park, Tae-Hwan KimAdditional file 3: Supplementary Figure 3. Analysis of WNT16 level in collected sera. The human WNT16 levels were measures in the collected sera (HC, n=3; AS, n=36) using ELISA. N.S., not significant.
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the national research foundation of korea
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osteoblast differentiation accompaniedassociated secretory phenotypeprimary osteoprogenitor cellsosteoprogenitor cells comparedwnt16 knockdown culturessasp mrna expressionisolated osteoprogenitor cellsinduced sasp expressionassess cell senescenceseven disease controlosteoprogenitor cellswnt16 expressionisolated usingcell senescencewnt16 treatmentvitro modelvitro assaysstill unknownstained markedlypathophysiological changesp21 proteinoutgrowth methodidentified rolehighly expressedh2o2 stressforming activityfacet jointsconclusion wnt16ankylosing spondylitisalso validated
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