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Additional file 3 of Long-term perturbation of the peripheral immune system months after SARS-CoV-2 infection

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posted on 2022-01-14, 05:09 authored by Feargal J. Ryan, Christopher M. Hope, Makutiro G. Masavuli, Miriam A. Lynn, Zelalem A. Mekonnen, Arthur Eng Lip Yeow, Pablo Garcia-Valtanen, Zahraa Al-Delfi, Jason Gummow, Catherine Ferguson, Stephanie O’Connor, Benjamin A. J. Reddi, Pravin Hissaria, David Shaw, Chuan Kok-Lim, Jonathan M. Gleadle, Michael R. Beard, Simon C. Barry, Branka Grubor-Bauk, David J. Lynn
Additional file 3: Figure S3: Adjusting for differences in immune cell populations. We repeated the differential expression analysis multiple times, each time adjusting for differences in the frequency of major immune cell populations among individuals. Each panel shows the enrichment of selected pathways (same as those shown in Fig. 4F) among genes identified as being significantly up-regulated in each analysis (FDR < 0.05 and fold change > 1.25-fold). None = no immune cell population adjustment.

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European Molecular Biology Laboratory Flinders Medical Centre Foundation The Women’s and Children’s Hospital Foundation The Hospital Research Foundation

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    BMC Medicine

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    SARS-CoV-2COVID-19ImmunityRNA-SeqT cellAntibody responsesConvalescent patientsImmunophenotypingLong COVIDPost-acute sequelae of COVID-19 (PASC)Post COVID-19 conditionInfection

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