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Additional file 2 of Establishment of an in vitro model for analyzing mitochondrial ultrastructure in PRKN-mutated patient iPSC-derived dopaminergic neurons

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posted on 2021-03-25, 08:40 authored by Mutsumi Yokota, Soichiro Kakuta, Takahiro Shiga, Kei-ichi Ishikawa, Hideyuki Okano, Nobutaka Hattori, Wado Akamatsu, Masato Koike
Additional file 2: Figure S1. Characterization of non-dopaminergic neurons differentiated from TH-GFP iPSC lines. Immunofluorescence staining for TH, β3-tubulin, and Nestin identified other neural subtypes (β3-tubulin + TH-) and neural progenitor cells (Nestin + TH-) among the non-dopaminergic cells derived from TH-GFP iPSC lines. Arrowheads indicate β3-tubulin + TH- or Nestin + TH- cells. “PRKN” represents PRKN-mutated patient. Scale bar, 20 µm.

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Japan Society for the Promotion of Science Ministry of Education, Culture, Sports, Science and Technology Japan Agency for Medical Research and Development Juntendo University

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    Molecular Brain

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    MitochondriaUltrastructurePRKNIPSCDopaminergic neurons

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