Additional file 1 of The use of direct oral anticoagulants for thromboprophylaxis or treatment of cancer-associated venous thromboembolism: a meta-analysis and review of the guidelines

Additional file 1 Table S1. Definitions of the outcomes for included studies. Fig. S1. Quality assessment of included randomized controlled trials. Fig. S2. Funnel plot for the VTE events outcome in the thromboprophylaxis studies. Fig. S3. Funnel plot for the symptomatic VTE events outcome in the thromboprophylaxis studies. Fig. S4. Funnel plot for the major bleeding events outcome in the thromboprophylaxis studies. Fig. S5. Funnel plot for the clinically relevant nonmajor bleeding events outcome in the thromboprophylaxis studies. Fig. S6. Funnel plot for the major or clinically relevant nonmajor bleeding events outcome in the thromboprophylaxis studies. Fig. S7. Funnel plot for the VTE recurrence outcome in the treatment studies. Fig. S8. Funnel plot for the major bleeding events outcome in the treatment studies. Fig. S9. Funnel plot for the clinically relevant nonmajor bleeding events outcome in the treatment studies. Fig. S10. Funnel plot for the major or clinically relevant nonmajor bleeding events outcome in the treatment studies. Fig. S11. Thromboprophylaxis results (DOACs vs. LMWH). Fig. S12. Thromboprophylaxis results (DOACs vs. placebo).