posted on 2021-09-26, 03:16authored byPhilipp Lassarén, Caroline Lindblad, Arvid Frostell, Keri L. H. Carpenter, Mathew R. Guilfoyle, Peter J. A. Hutchinson, Adel Helmy, Eric Peter Thelin
Additional file 1. Title of data: Baseline data. Description of data: Columns for the first eight rows are for each patient (C, control; I, intervention); moreover, the first four rows have time along the horizontal axis. Columns for the final row are for each cytokine. Rows 1-3 display changes over time of white cell count (WCC), C-reactive protein (CRP) and temperature, with corresponding lines of best fit. Row 4 displays infection status of patients over time. Row 5 shows infection (VAP, ventilator-associated pneumonia; IAS intra-abdominal sepsis; CI, chest infection), severe adverse events (SAE), sex (M, male; F, female) and years of age for each patient. Row 6 shows Stockholm computed tomography (CT) score for each patient, coloured after whether a deterioration was observed during hospital stay. Row 7 shows injury severity score (ISS) for each patient. Row 8 shows fraction of missingness in each compartment and for each patient. Row 9 shows fraction of missing cytokines in each compartment. The chest infection was a result of mucous plugging resulting in a right lower lobe collapse, hence not fulfilling VAP criteria.
Funding
Swedish Brain Foundation Karolinska Institutet Region Stockholm National Institute for Health Research Biomedical Research Centre, Cambridge (Neuroscience Theme; Brain Injury and Repair Theme) National Institute for Health Research (NIHR) NIHR Cambridge Biomedical Research Centre NIHR Global Health Research Group on Neurotrauma a European Union Seventh Framework Program grant (Collaborative European NeuroTrauma Effectiveness Research in TBI [CENTER-TBI]) Royal College of Surgeons of England Royal College of Surgeons of England Pump Priming Grant MRC/Royal of Surgeons of England Clinical Research Training Fellowship MRC Grant Swedish Society for Medical Research StratNeuro Stockholms Läns Landsting Karolinska Institute