Additional file 1 of Serum biomarkers of the calcium-deficient rats identified by metabolomics based on UPLC/Q-TOF MS/MS

Additional file 1: Sup Table 1 The gradient elution procedures of UPLC in the positive and negative ion mode. Sup Table 2 Reproducibility of method from 5 ions of all samples in the positive mode. Sup Table 3 Reproducibility of method from 5 ions of all samples in the positive mode. Sup Table 4 The differential variables of calcium deficiency in positive ion mode by EZ-info software. Sup Table 5 The differential variables of calcium deficiency in negative ion mode by EZ-info software. Sup Table 6 The differential variables of calcium deficiency in negative ion mode by MetaboAnalystR. Sup Table 7 The differential variables of calcium deficiency in negative ion mode by MetaboAnalyst. Sup Table 8 Summary of pathway analysis with MetaboAnalyst. Sup Figure 1 Overlap of all total ion chromatographic of all serum samples. Sup Figure 2 The PCA and PLS-DA score plots of analysis of the LCG and NCG with MetaboAnalystR. Sup Figure 3 MSMS spectrum of biomarkers.