Additional file 1 of Rapid intrapartum test for maternal group B streptococcal colonisation and its effect on antibiotic use in labouring women with risk factors for early-onset neonatal infection (GBS2): cluster randomised trial with nested test accuracy study
posted on 2022-01-14, 05:07authored byJane P. Daniels, Emily Dixon, Alicia Gill, Jon Bishop, Mark Wilks, Michael Millar, Jim Gray, Tracy E. Roberts, Jane Plumb, Jonathan J. Deeks, Karla Hemming, Khalid S. Khan, Shakila Thangaratinam
Additional file 1 : Table S1. Antibiotic administration by GBS rapid test result. Table S2. Provision of antibiotic for different clinical reasons, by GBS test result. *Women can have more than one reason given for receiving intrapartum antibiotics. Table S3. Maternal antibiotic use in rapid test and usual care maternity units. *Unadjusted analysis due to lack of convergence with the adjusted model. **Estimated through an adjusted Poisson model with robust standard errors, estimates should be interpreted with caution as the covariance matrix for the random effects is not positive definite. Table S4. Use of GBS intrapartum antibiotic prophylaxis by risk factor subgroups. Table S5. Comparison of the reasons for neonatal antibiotic administration. *For 85 babies, there were >1 reason for receiving antibiotics; ^ For 129 babies, there were >1 reasons for receiving antibiotics; N is number of babies who received antibiotics and indication provided. Table S6. Management of babies administered IV antibiotics for suspected early neonatal sepsis. Table S7. Sensitivity analysis of accuracy of rapid test to diagnose GBS colonisation. Table S8. Prevalence of GBS maternal colonisation by test.