Additional file 1 of Plitidepsin as a successful rescue treatment for prolonged viral SARS-CoV-2 replication in a patient with previous anti-CD20 monoclonal antibody-mediated B cell depletion and chronic lymphocytic leukemia

Additional file 1. Text summarizes methods used, analytical procedures, complications, therapies prescribed during hospitalization and further considerations; Table 1S–4S show analytical parameters that include: absence of immunoresponse against SARS-CoV-2; an increase in lymphocytic populations over time and serum biochemical results during the clinical event. A summary of ISARIC mortality score is also shown. Figure 1S Timeline of qPCR Ct over time, patient shows a reduction in the viral load after the treatment with the second cycle of plitidepsin. Figure 2S Bilateral pneumonia improvement after plitidepsin treatment determined by thorax imagen.