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Additional file 1 of METTL1 mediated tRNA m7G modification promotes leukaemogenesis of AML via tRNA regulated translational control

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posted on 2024-01-25, 05:00 authored by Pan Zhao, Lin Xia, Dan Chen, Wei Xu, Huanping Guo, Yinying Xu, Bingbing Yan, Xiao Wu, Yuxia Li, Yunfang Zhang, Xi Zhang
Additional file 1: Figure S1. METTL1/WDR4 were upregulated in AML patients. (A-B) Comparison of METTL1 and WDR4 expression in healthy donors and WHO subtypes of AML patients from our center. (C-D) Comparison of METTL1 and WDR4 expression in healthy individuals (NC) and WHO subtypes of AML patients from GEO dataset. Data were presented as mean ± SD (Student’s t test, *p < 0.05, **p < 0.01, ns: not significant).

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Natural Science Foundation of Sichuan Province National Natural Science Foundation of China Natural Science Foundation Project of Chongqing, Chongqing Science and Technology Commission Fundamental Research Funds for the Central Universities

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    Experimental Hematology & Oncology

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    METTL1/WDR4tRNA modificationm7GAMLTranslation control

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