Additional file 1 of Identification of four novel hub genes as monitoring biomarkers for colorectal cancer

Additional file 1: Supplemental Figure 1. Sample dendrogram and trait heatmap. Supplemental Figure 2. Heat map for top 20 down-regulated and top 20 up-regulated genes. Note: The gene symbols were listed in Y-axis and the datasets were listed in X-axis. Color-coded according to correlation coefficient (legend at right). Supplemental Figure 3. Cluster dendrogram. Note: Module identification is based on gene expression similarity. The genes with similar expression clustered according to a topological overlap metric into modules; assigned modules were colored and uncharacteristic genes assigned to gray module. Supplemental Figure 4. The scatter diagram between the module membership in yellow module and gene significance for disease. Supplemental Figure 5. A-D DNA methylation of 4 top hub genes based on colon adenocarcinoma (COAD). Supplemental Figure 6. A-D DNA methylation of 4 top hub genes based on rectum adenocarcinoma (READ).