Additional file 1 of Blocking of efflux transporters in rats improves translational validation of brain radioligands

Shalgunov, Vladimir; Xiong, Mengfei; L’Estrade, Elina T.; Raval, Nakul R.; Andersen, Ida V.; Edgar, Fraser G.; Speth, Nikolaj R.; Baerentzen, Simone L.; Hansen, Hanne D.; Donovan, Lene L.; Nasser, Arafat; Peitersen, Siv T.; Kjaer, Andreas; Knudsen, Gitte M.; Syvänen, Stina; Palner, Mikael; Herth, Matthias M.

doi:10.6084/m9.figshare.13114890.v1

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Additional file 1 of Blocking of efflux transporters in rats improves translational validation of brain radioligands

journal contribution

posted on 2020-10-20, 03:38 authored by Vladimir Shalgunov, Mengfei Xiong, Elina T. L’Estrade, Nakul R. Raval, Ida V. Andersen, Fraser G. Edgar, Nikolaj R. Speth, Simone L. Baerentzen, Hanne D. Hansen, Lene L. Donovan, Arafat Nasser, Siv T. Peitersen, Andreas Kjaer, Gitte M. Knudsen, Stina Syvänen, Mikael Palner, Matthias M. Herth

Additional file 1. Detailed overview of the experimental design, description of experiments in pigs, chemical structures of all studied compounds, investigated brain regions on the MRI template, time–activity curves for rat and pig ([18F]Fallypride and [11C]BA-10) scans, SBR and AUC values for all tracers, numbers of rats scanned per experimental condition are detailed in the Additional file.