Activated CD4+CD25^hiFoxP3- lymphocytes.

HW+: hookworm infected subjects, HW-: control subjects. 2W: 2 weeks, 1M: 1 month, 3M: 3 months and 12M: 12 months after treatment. HW+ group is represented with black square with continuous lines and HW- group with a blank circle with discontinuous lines. To compare the HW+ and HW- groups and their evolution, a maximum likelihood analysis has been used to test a group (HW), a time (T) and a group * time (HW * T) interaction effects (with data at T0, 2W and 1M). Statistical results are summarized in correspondent tables for each parameter. To compare longitudinal data from the HW+ group (T0, 2W, 1M, 3M and 12M), a time and a time² effects were tested. The time effect is depicted on the figures and the time² effect is given in the results section (* p<0.05, ** p<0.01, ***p<0.001).

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