ol0705999_si_001.pdf (310.63 kB)
Abyssomicin E, a Highly Functionalized Polycyclic Metabolite from Streptomyces Species#
journal contribution
posted on 2007-06-21, 00:00 authored by Xue-Mei Niu, Sheng-Hong Li, Helmar Görls, Dieter Schollmeyer, Matthias Hilliger, Susanne Grabley, Isabel SattlerAbyssomicin E (1), a new polycyclic metabolite with a C19 skeleton, was isolated from Streptomyces sp. (HKI0381). Its chemical structure was
determined by comprehensive NMR and MS spectroscopic analyses. For the first time in this recently discovered class of compounds, the
absolute stereochemistry was directly established by subsequent single-crystal X-ray diffraction study using anomalous dispersion with copper
radiation.