pcbi.1008904.g002.tif (735.37 kB)
KIR sequence characterization before and after imputation.
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posted on 2021-08-02, 17:39 authored by Wesley M. Marin, Ravi Dandekar, Danillo G. Augusto, Tasneem Yusufali, Bianca Heyn, Jan Hofmann, Vinzenz Lange, Jürgen Sauter, Paul J. Norman, Jill A. Hollenbach(A) Histogram of IPD-KIR allele sequence lengths, shown as percentage of longest sequence for each gene and major allele group. (B) Histogram of IPD-KIR allele sequence lengths after imputation, shown as percentage of longest sequence for each gene and major allelic group.
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short-read sequencing datacustom alignment processing workflowcopy number determination performancekiller-cell immunoglobulin-like rec...KIR gene copy number classification...high-throughput KIR genotypinggenotype determination workflowKIR genesgenotype determination performanceKiller-cell Immunoglobulin-like Rec...chromosome 19 encodes receptorsAfrican validation cohortshigh-throughput KIR sequence analysisnovel alignment strategiesgenotype determination accuracygene copy numberhigh-fidelity sequencing method
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