pone.0262046.g001.tif (171.73 kB)
In vivo tolerability evaluation with modified McDonald Shadduck scoring (mMS).
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posted on 2022-01-10, 18:23 authored by Allison A. Fuchs, Praveen K. Balne, Elizabeth A. Giuliano, Nishant R. Sinha, Rajiv R. MohanIn safety evaluation, no significant difference in mMS scores between naïve eyes of Group-2 and unwounded eyedrop-treated eyes of Group-4 up to 28 days was observed. Conversely, alkali wounded eyes of Group-1 showed significant difference in mMS compared to the eyes of Group-3 at day-14 and day-28 (n = 6 for each group; @ = p value <0.01; # = p value <0.001).
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