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CTEN stimulates the expression of TGF-β1 in A549 and NCI-H1299 cells.

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posted on 2018-07-09, 17:26 authored by Xiangdong Lu, Juan Gao, Yao Zhang, Tao Zhao, Hongchuan Cai, Tingrong Zhang

Western blot and Eliseanalysis showing that overexpression of CTEN signifcantly enhanced the expression TGF-β1 and the downstream signaling pathway(A-B). Silencing of CTEN signifcantly suppressed the expression of TGF-β1 as well as the downstream effectors Smad2, p-Smad2 and α-SMA (C-D). *P<0.05, **P<0.01, vs. Control.

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