Waveforms for ERG of ASP-treated retina, and for ERG and CAP of saline-treated retina.

(A) Waveforms of electroretinogram (ERG) of aspartate (ASP)-treated retina, (B) ERG of saline (S)-treated retina, and (C) compound action potential (CAP) of S-treated retina at increasing irradiance levels. Stimulus irradiance was incremented in 0.3 log unit steps. The ERG a-wave from ASP-treated retina was used to estimate the photoresponse of cones; the ERG b-wave from S-treated retina was used to estimate the light-evoked response of the output of cones; and the ON response of CAP from S-treated retina was used to estimate the light-evoked response of the optic nerve. Note that individual waveforms were vertically displaced for clarity of presentation. Horizontal thick lines indicate the time and duration of the light stimulus.