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Tracer distribution of 68Ga-DOTATATE in GBM.
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posted on 2015-03-25, 04:15 authored by Constantin Lapa, Thomas Linsenmann, Katharina Lückerath, Samuel Samnick, Ken Herrmann, Carolin Stoffer, Ralf-Ingo Ernestus, Andreas K. Buck, Mario Löhr, Camelia-Maria MonoranuThree examples of increased 68Ga-DOTATATE uptake in Glioblastoma multiforme. Markedly, partly inhomogeneous tracer accumulation can be depicted in each patient. Shown are axial views of CT, SSTR-PET as well as fused PET/CT images.
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tamtracerSSTR 2A expressionresident microgliaSSTR 2A immunostainingPositron emission tomographyresident microglial cellsGBM.Methods 15 samplestumor cellsSomatostatin receptor imagingDOTATATEglioma cellssomatostatin receptor 2cell surfacemacrophageimmunohistochemical staining patterns.ConclusionSSTR 2A
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