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The Hitchhiking Index.
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posted on 2015-09-17, 02:48 authored by Jasmine Foo, Lin L Liu, Kevin Leder, Markus Riester, Yoh Iwasa, Christoph Lengauer, Franziska MichorProbability of detecting the passenger mutation in x out of 220 patients for a variety of values q, which represents the probability that the candidate mutation ‘A’ is present in a sufficiently large fraction of the final population size to be detected.
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subsetprioritizingcolorectal cancercandidate genefitness advantagetumorigenesiprioritizationdistinguishingEvolutionary Approachmutation accumulationpopulation dynamics modelprobabilitydatamethodologydrug discoverycancer sampleHitchhiking Indexpassenger alterationcancer initiationgenomic landscapecandidate mutationsaidsequencingeffortcolorectal tissuevalidationfrequencycancer typesdriver mutations
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