Figure_3.tif (333.93 kB)
Download file

The HCP clusters are more robust against perturbations to its architecture than the SCP clusters.

Download (0 kB)
posted on 2013-02-21, 11:44 authored by Aparna Nittala, Soumitra Ghosh, Xujing Wang

At normal coupling strength of gc = 200 pS (left columns), both cluster types are robust against up to 50% β-cell loss in the cluster. When the coupling is compromised with reduced gc values (middle and right columns), the SCP clusters are more affected by β-cell loss. Dashed lines are the mean and the 2 standard deviations (SD) of completely uncoupled β cells.