Figure_8.tif (68.28 kB)
Summary diagram of the actions of NGF.
figure
posted on 2010-02-02, 01:33 authored by Jaehoon Chung, Hiroyuki Kubota, Yu-ichi Ozaki, Shinsuke Uda, Shinya KurodaThe first transient NGF stimulation drives the latent process via ERK and transcription activities, while the second sustained NGF stimulation drives the fast extension process via ERK and PI3K activities. Thus, NGF induces cell differentiation via two temporally and mechanistically distinct processes.
