Sequence logo for acceptor splice sites: splice sites have quite strong consensus sequences, i.e., almost every position in a small window around the splice site is representative of the most frequently occurring nucleotide when many existing sequences are compared in an alignment.
posted on 2013-02-21, 07:41authored byAsa Ben-Hur, Cheng Soon Ong, Sören Sonnenburg, Bernhard Schölkopf, Gunnar Rätsch
The sequence logo [72],[73] shows the region around the intron/exon boundary—the acceptor splice site. In the running example, we use the region up to 40 nt upstream and downstream of the consensus site AG.