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Sensitivity of JUNV to IFN pretreatment.

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posted on 2012-05-22, 01:31 authored by Cheng Huang, Olga A. Kolokoltsova, Nadezdha E. Yun, Alexey V. Seregin, Allison L. Poussard, Aida G. Walker, Allan R. Brasier, Yingxin Zhao, Bing Tian, Juan Carlos de la Torre, Slobodan Paessler

Vero cells were treated with IFN-α, β or γ at the indicated concentrations for 8 h and then infected with Romero JUNV (A) or Candid#1 JUNV (B) at an MOI of 0.1. At 2 days p.i., supernatants were collected and assayed for virus production by plaque assay. Due to the severe cytotoxicity caused by IFN-γ treatment at 2000 U/ml, virus infection was not performed at this condition. Data represent the average of three replicates ±SEM.


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