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Representative arterial input functions (A) and tumor signal enhancement curves (B) at baseline and follow-up. Signal intensity [HU, Hounsfield Units] (y-axis) is displayed over time [s] (x-axis).

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posted on 30.09.2013, 03:06 authored by Clemens C. Cyran, Philipp M. Kazmierczak, Heidrun Hirner, Matthias Moser, Michael Ingrisch, Lukas Havla, Alexandra Michels, Ralf Eschbach, Bettina Schwarz, Maximilian F. Reiser, Christiane J. Bruns, Konstantin Nikolaou

Note the almost identical arterial input functions for baseline and follow-up which can be considered a marker of good reproducibility of individual perfusion scans. After anti-angiogenic therapy, a decline in tumor signal enhancement due to reduced tumor perfusion was observed.