Figure_1.tif (2.07 MB)
PPARγ expression is induced in bone-marrow derived monocytes after infection with Listeria monocytogenes.
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posted on 2012-05-21, 01:27 authored by Zeinab Abdullah, Sergej Geiger, Andrea Nino-Castro, Jan P. Böttcher, Eugenia Muraliv, Moritz Gaidt, Frank A. Schildberg, Kati Riethausen, Juliane Flossdorf, Wolfgang Krebs, Trinad Chakraborty, Christian Kurts, Joachim L. Schultze, Percy A. Knolle, Luisa Klotz(A) Time course of PPARγ expression in human monocytes following Listeria monocytogenes infection detected by Western blot. (B) PPARγ target genes (n = 80) with the most significant differential expression in human macrophages post infection. Gene expression differences (log scale) are visualized as a heat map following hierarchical clustering of rows and columns (red = increased expression). (C,D) Time course of PPARγ expression in bone marrow derived macrophages (BMDM) post infection detected by Western blot or immunohistochemistry. (blue = DAPI staining the cell nucleus and Listeria DNA; green = PPARγ).
